Why BOV (Bag On Valve) Technology

Bag-on-valve- manufacturing process

Aspects	BOV	Traditional jets / Sprays
Product Emptying	Up to 100%	Less than 80%
Product waste	0%	Over 20% waste
Storage	Aluminum can, durable & easy to handle and store	Mainly plastic bottles, caps are vulnerableto unscrewing, damage & contamination
Pack convenience	Air pressurized, pressure is not compromised over continuous use	Plastic caps, Easily unscrewed & Vulnerable for contamination
Contamination	No chance for active ingredients contamination	Active ingredient are vulnerable for contamination
Application	Incredible 360 degrees easily applied in any angle, Perfect coverage for nasal cavities and (Hard-to-reach) skin folds	Horizontal application only, drug will not reach nasal cavities or skin folds properly
Oil-based Products	Excellent coverage, No need to rub	No suitable, Always need to rub
Patient dependency	Patient can apply the product independently even for the (Difficult to reach) skin folds	Patient is usually dependent on nurses / HCPs to apply medication, especially diabetic foot and wounds patients

Aspects	BOV	Traditional Aerosol
Product Emptying	Up to 100%	Less than 80%
Product waste	0%	Over 20% waste
Flammability	No flammable, easily handling & strong condition	Flammable & need cautious handling and storage condition
Additives & Preservatives	No additives, drug is separated in a bag	Mixed with preservatives & propellent gases, usually compromise drug bioavailability
Product type	Water -based, oil-based, gels & foams	Mainly water-based products
Contamination	No chance for active ingredients contamination	Active ingredients are vulnerable for contamination inside the can because of the additives
Application	Incredible 360 degrees easily applied in any angle, perfect coverage for nasal cavities and (Difficult-to-reach) skin folds	Horizontal application only, drug will not reach nasal cavities or skin folds properly due to compromised pressure
Patient convenience	No stinging or burning sensation as pressure can be optimized within manufacturing process	Persistent stinging & burning sensation due to propellants